modified nucleobases Search Results


nucleobase-modified pna  (Chemie GmbH)
90
Chemie GmbH nucleobase-modified pna
Nucleobase Modified Pna, supplied by Chemie GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/modified+nucleobases/10__1002_slash_anie__201511038-1-13-5?v=Chemie+GmbH
Average 90 stars, based on 1 article reviews
nucleobase-modified pna - by Bioz Stars, 2026-07
90/100 stars
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nucleobase modifiers  (Verlag GmbH)
90
Verlag GmbH nucleobase modifiers
Nucleobase Modifiers, supplied by Verlag GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/modified+nucleobases/10__1002_slash_ange__202082811-93-7-27?v=Verlag+GmbH
Average 90 stars, based on 1 article reviews
nucleobase modifiers - by Bioz Stars, 2026-07
90/100 stars
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modified nucleobases  (Alloc Modulo LTD)
90
Alloc Modulo LTD modified nucleobases
Modified Nucleobases, supplied by Alloc Modulo LTD, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/modified+nucleobases/us10160787-142-43-22?v=Alloc+Modulo+LTD
Average 90 stars, based on 1 article reviews
modified nucleobases - by Bioz Stars, 2026-07
90/100 stars
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modified nucleobases  (SomaLogic)
90
SomaLogic modified nucleobases
Schematic of SELEX and modification of DNA/RNA library for SELEX. (A) Flowchart of SELEX procedure. (B) Modified oligonucleotide library employed in SELEX selection. Nucleotide substitution on the 2′-carbon of ribose, on the 5′-α-P-site, or artificial riboses were introduced in the modified library to generate aptamers with enhanced nuclease-resistance. Modified <t>nucleobases</t> and artificial nucleobases were introduced to increase functionality or information density. (C) Groups mimicking amino acid side chains are added on C5-modified deoxyuridines to increase functionality in the initial library. SomaLogic uses these modified nucleobases to generate aptamers with enhanced binding affinity. (D) Extended genetic nucleobases (Z and P, Px and Ds) and their structural comparison with natural nucleobases. Introduction of artificial nucleobases increases information density in the initial library in addition to adding functionality.
Modified Nucleobases, supplied by SomaLogic, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/modified+nucleobases/pmc05519284-60-4-0?v=SomaLogic
Average 90 stars, based on 1 article reviews
modified nucleobases - by Bioz Stars, 2026-07
90/100 stars
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phosphane-modified nucleobases 6–8  (Verlag GmbH)
90
Verlag GmbH phosphane-modified nucleobases 6–8
Schematic of SELEX and modification of DNA/RNA library for SELEX. (A) Flowchart of SELEX procedure. (B) Modified oligonucleotide library employed in SELEX selection. Nucleotide substitution on the 2′-carbon of ribose, on the 5′-α-P-site, or artificial riboses were introduced in the modified library to generate aptamers with enhanced nuclease-resistance. Modified <t>nucleobases</t> and artificial nucleobases were introduced to increase functionality or information density. (C) Groups mimicking amino acid side chains are added on C5-modified deoxyuridines to increase functionality in the initial library. SomaLogic uses these modified nucleobases to generate aptamers with enhanced binding affinity. (D) Extended genetic nucleobases (Z and P, Px and Ds) and their structural comparison with natural nucleobases. Introduction of artificial nucleobases increases information density in the initial library in addition to adding functionality.
Phosphane Modified Nucleobases 6–8, supplied by Verlag GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/modified+nucleobases/10__1002_slash_ejoc__201000125-51-3-9?v=Verlag+GmbH
Average 90 stars, based on 1 article reviews
phosphane-modified nucleobases 6–8 - by Bioz Stars, 2026-07
90/100 stars
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nucleobase modified mir 122 mimics  (Sirna Therapeutics)
86
Sirna Therapeutics nucleobase modified mir 122 mimics
Schematic of SELEX and modification of DNA/RNA library for SELEX. (A) Flowchart of SELEX procedure. (B) Modified oligonucleotide library employed in SELEX selection. Nucleotide substitution on the 2′-carbon of ribose, on the 5′-α-P-site, or artificial riboses were introduced in the modified library to generate aptamers with enhanced nuclease-resistance. Modified <t>nucleobases</t> and artificial nucleobases were introduced to increase functionality or information density. (C) Groups mimicking amino acid side chains are added on C5-modified deoxyuridines to increase functionality in the initial library. SomaLogic uses these modified nucleobases to generate aptamers with enhanced binding affinity. (D) Extended genetic nucleobases (Z and P, Px and Ds) and their structural comparison with natural nucleobases. Introduction of artificial nucleobases increases information density in the initial library in addition to adding functionality.
Nucleobase Modified Mir 122 Mimics, supplied by Sirna Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/modified+nucleobases/pham_kevin__2022__studies_of_chemically_modified_oligonucleotides_towards_rna_binding_proteins-47-25-19?v=Sirna+Therapeutics
Average 86 stars, based on 1 article reviews
nucleobase modified mir 122 mimics - by Bioz Stars, 2026-07
86/100 stars
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Image Search Results


Schematic of SELEX and modification of DNA/RNA library for SELEX. (A) Flowchart of SELEX procedure. (B) Modified oligonucleotide library employed in SELEX selection. Nucleotide substitution on the 2′-carbon of ribose, on the 5′-α-P-site, or artificial riboses were introduced in the modified library to generate aptamers with enhanced nuclease-resistance. Modified nucleobases and artificial nucleobases were introduced to increase functionality or information density. (C) Groups mimicking amino acid side chains are added on C5-modified deoxyuridines to increase functionality in the initial library. SomaLogic uses these modified nucleobases to generate aptamers with enhanced binding affinity. (D) Extended genetic nucleobases (Z and P, Px and Ds) and their structural comparison with natural nucleobases. Introduction of artificial nucleobases increases information density in the initial library in addition to adding functionality.

Journal: Journal of the American Chemical Society

Article Title: Molecular Elucidation of Disease Biomarkers at the Interface of Chemistry and Biology

doi: 10.1021/jacs.6b10646

Figure Lengend Snippet: Schematic of SELEX and modification of DNA/RNA library for SELEX. (A) Flowchart of SELEX procedure. (B) Modified oligonucleotide library employed in SELEX selection. Nucleotide substitution on the 2′-carbon of ribose, on the 5′-α-P-site, or artificial riboses were introduced in the modified library to generate aptamers with enhanced nuclease-resistance. Modified nucleobases and artificial nucleobases were introduced to increase functionality or information density. (C) Groups mimicking amino acid side chains are added on C5-modified deoxyuridines to increase functionality in the initial library. SomaLogic uses these modified nucleobases to generate aptamers with enhanced binding affinity. (D) Extended genetic nucleobases (Z and P, Px and Ds) and their structural comparison with natural nucleobases. Introduction of artificial nucleobases increases information density in the initial library in addition to adding functionality.

Article Snippet: SomaLogic uses these modified nucleobases to generate aptamers with enhanced binding affinity. (D) Extended genetic nucleobases (Z and P, Px and Ds) and their structural comparison with natural nucleobases.

Techniques: Modification, Selection, Binding Assay, Comparison